The Production of an Antifungal Antibiotic by Streptomyces griseus
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چکیده
منابع مشابه
Oxidation of Meloxicam by Streptomyces griseus
The aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. Among the actinomycetes screened, Streptomyces griseus NCIM 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in S. griseus NCIM 2623...
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Cycloheximide accumulation in a fermentation medium has been shown to be the product of the balance between synthesis and degradation of this antibiotic. Glucose has been shown to prevent cycloheximide degradation. Cycloheximide has been shown to interfere with its own synthesis probably due to feedback inhibition. Approaches for increasing cycloheximide titers in the light of these findings ar...
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The present study is concerned with the production of antitumor antibiotic by Streptomyces capoamus in batch fermentation. Antibiotic activity was tested against Bacillus subtilis by cylinder plate method. Different culture media were screened and M3 medium consisting of glucose (10.0 g/L), yeast extract (1.0 g/L), meat extract (4.0 g/L), peptone (4.0 g/L) and NaCl (2.0 g/L) was found to be the...
متن کاملoxidation of meloxicam by streptomyces griseus
the aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. among the actinomycetes screened, streptomyces griseus ncim 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in s. griseus ncim 2623...
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The biosynthesis of chromomycin A3 was investigated using 13C-labeled acetates, methionine and glucose, and 13C,18O-labeled acetate. 13C NMR spectral analysis demonstrated that: Aglycone assembly occurs by combining at least two polyketide chains; three of nine oxygen atoms of the aglycone originate from acetate precursor oxygen atoms; carbon methylations on the aromatic ring at C-7, on the chr...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1946
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.52.5.610-611.1946